Article Abstract

Posner-Schlossman syndrome: a 10-year review of clinical experience

Authors: Ling Wang, Gang Yin, Dabo Wang, Zhiying Yu

Abstract

Background: To describe our 10-year experience with Posner-Schlossman syndrome (PSS) in terms of morbidity and prognosis.
Methods: We investigated 72 cases (74 eyes; both eyes of 2 cases) of PSS between July 2005 and July 2015. Data were collected on intraocular pressure (IOP), keratic precipitates (KP), anterior chamber, pupil, optic nerve disc and visual field, as well as general characteristics. Each case was examined every 3 to 7 days during attacks and every 2 to 6 months between attacks.
Results: The mean age of the 72 patients (41 men) was 40±6 years (range, 16–64 years). The mean disease duration was 4.3 years (range, 1–7 years) and mean follow-up 4.9 years (range, 1–8 years). Medical treatment was efficacious for 62 patients (62 eyes, 83.78%). Ten patients exhibited progressive cupping and visual field loss (12 eyes, 16.22%), all had normal IOP and no recurrence of PSS after trabeculectomy with anti-metabolite treatment.
Conclusions: Although the prognosis of most PSS is usually benign, the IOP and optic nerve disc must be monitored. Visual-field damage can occur with long-term disease and frequent attacks.

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