The Handan Offspring Myopia Study

Caixia Lin, Ningli Wang


The Handan Offspring Myopia Study (HOMS), whose participants came from 6 villages where all people aged ≥30 years had taken part in the Handan Eye Study (HES) in 2006–2007, was designed to obtain the familial associations of myopia between parents and their offspring. From March 2010 to June 2010, of 1,238 eligible individuals, 878 children (70.2%; 52.6% male) from 541 families were recruited. The mean age of the children was 10.5±2.5 years. All the participants had a detailed eye examination and anthropometry examination. All examinations were performed using the same protocols and equipment in both HES and HOMS. Information of the parents was obtained from the HES. The results of the research showed that the myopic shift from parents to children was estimated to be approximately 1 D at 18 years of age. For near work and myopia, no association was found, except for the high near work subgroup with moderate outdoor activity levels. Besides a weak protective effect of outdoor activity on myopia in these rural children was observed. In the future, we plan to follow up these participants and investigate how the refraction of the children change, how myopia-genic activity changes and what effect does it have on myopia. The information will be important for the design of strategies to prevent and reduce myopia.