Focused Issue on Retinal Imaging and Diagnostics

Posted On 2020-01-15 11:20:48


This focused issue on “Retinal Imaging and Diagnostics” is edited by Roland Theodore Smith, MD, PhD, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.

Roland Theodore Smith, MD, PhD
Icahn School of Medicine at Mount Sinai, New York, NY
New York Eye and Ear Infirmary of Mount Sinai, New York, NY

R Theodore (Ted) Smith MD PhD is Professor of Ophthalmology and Neuroscience in the ISMMS and Director of Biomolecular Retinal Imaging at the NYEEI. He graduated summa cum laude, Phi Beta Kappa from Rice University with a BA in mathematics, then earned his PhD in the mathematics of curved Riemannian spaces as a Marshall scholar in England, followed by faculty positions in mathematics at MIT and Columbia.

He attended med school at the Albert Einstein COM, graduating AOA, did his ophthalmology residency and chief residency at Columbia, and retina fellowship at the U of Illinois under Morton Goldberg. He returned to Columbia, rising to Professor of Clinical Ophthalmology and Biomedical Engineering, and leading the Columbia Macular Genetics study, which discovered genes for age-related macular degeneration (AMD). He was recruited to NYU as Director of Vision Research, and then by Professor James Tsai to ISMMS.

Dr. Smith’s R01 funded research, and his 30 years’ experience as a medical retinal specialist, both emphasize advanced retinal imaging. He invented quantitative autofluorescence (qAF) imaging by modifying a scanning laser ophthalmoscope, then hyperspectral AF imaging to identify the spectral signatures of individual compounds in complex biological systems, advancing his concept of biomolecular imaging to identify targets for therapeutic intervention. His clinical AMD research has also focused on the connections between subretinal deposits, choroidal insufficiency and systemic vascular disease. He has also recently used deep learning from big data for automated screening of AMD and predictive modeling of disease progression.

Focused issue outline:

  1. Introduction to the focused issue
  2. Review of crystalline retinopathies and OCTA
  3. The longitudinal analysis of quantitative biomarkers using projection-resolved optical coherence tomography angiography in retinal vein occlusions
  4. Telemedicine for Diabetic Retinopathy
  5. Annular Array Ultrasound
  6. Sub threshold lasers
  7. Structural Imaging of Inherited Retinal Diseases
  8. AF imaging of drusen and AMD deposits ex vivo
  9. Hyperspectral imaging
  10. Choriocapillaris in dry AMD as evaluated by OCT Angiography
  11. Advances in Adaptive Optics imaging
  12. Comment: bleaching of photoreceptors in eyes with RPD
  13. Super Resolution Imaging of RPE granules