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Clinical differences between young and older patients with optic neuritis

	author = {Wenjing Luo and Qiu-Shui Huang and Jian-Feng He and Min Han and Bo Liu and Yi Du},
	title = {Clinical differences between young and older patients with optic neuritis},
	journal = {Annals of Eye Science},
	volume = {2},
	number = {10},
	year = {2017},
	keywords = {},
	abstract = {Background: To compare clinical features in young (18–44 years) and older patients (>44 years) with optic neuritis (ON).
Methods: This is a retrospective case series study. One hundred thirty-three young cases and 51 older cases diagnosed with ON were reviewed.
Results: The older patients had lower proportion of disc swelling (37.3% vs. 57.1%, P=0.016), but higher proportion of brain plaques (21.6% vs. 7.5%, P=0.007) compared with the young patients. The proportion of patients suffered from hypertension or hyperglycemia was nearly 6 times higher in the older patients than in the young patients (29.4% vs. 5.3%, P44 years). Physicians should pay attention to the side effects of corticosteroids in elderly patients in clinical practice, although they are generally safe.},
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