TY - JOUR AU - Luo, Wenjing AU - Huang, Qiu-Shui AU - He, Jian-Feng AU - Han, Min AU - Liu, Bo AU - Du, Yi PY - 2017 TI - Clinical differences between young and older patients with optic neuritis JF - Annals of Eye Science; Vol 2 (October 2017): Annals of Eye Science Y2 - 2017 KW - N2 - Background: To compare clinical features in young (18–44 years) and older patients (>44 years) with optic neuritis (ON). Methods: This is a retrospective case series study. One hundred thirty-three young cases and 51 older cases diagnosed with ON were reviewed. Results: The older patients had lower proportion of disc swelling (37.3% vs . 57.1%, P=0.016), but higher proportion of brain plaques (21.6% vs . 7.5%, P=0.007) compared with the young patients. The proportion of patients suffered from hypertension or hyperglycemia was nearly 6 times higher in the older patients than in the young patients (29.4% vs . 5.3%, P Conclusions: There are some distinct differences between young patients (18–44 years) and older patients (>44 years). Physicians should pay attention to the side effects of corticosteroids in elderly patients in clinical practice, although they are generally safe. UR - https://aes.amegroups.org/article/view/3862