%0 Journal Article %T Shunting, optic nerve sheath fenestration and dural venous stenting for medically refractory idiopathic intracranial hypertension: systematic review and meta-analysis %A Scherman, Daniel B. %A Dmytriw, Adam A. %A Nguyen, Gia Thanh %A Nguyen, Nhan Thi %A Tchantchaleishvili, Nana %A Maingard, Julian %A Asadi, Hamed %A Brooks, Mark %A Griessenauer, Christoph %A Ogilvy, Christopher %A Thomas, Ajith J. %A Moore, Justin M. %A Phan, Kevin %J Annals of Eye Science %D 2018 %B 2018 %9 %! Shunting, optic nerve sheath fenestration and dural venous stenting for medically refractory idiopathic intracranial hypertension: systematic review and meta-analysis %K %X Background: Cerebrospinal fluid (CSF)-diversion procedures have traditionally been the standard of treatment for patients with medically refractive idiopathic intracranial hypertension (IIH). However, dural venous sinus stent (VSS) placement has been described as a safe and effective procedure for the management of medically refractive IIH. We performed a meta-analysis comparing outcomes and complications of CSF-diversion procedures, VSS and optic nerve sheath fenestration (ONSF) for the treatment of medically refractive IIH. Methods: Electronic searches were performed using six databases from 1988 to January 2017. Data was extracted and meta-analysed from the identified studies. Results: From 55 pooled studies, there were 538 CSF-diversion cases, 224 dural venous stent placements, and 872 ONSF procedures. Similar improvements were found in terms of postoperative headaches (CSF vs . VSS vs . ONSF: 84% vs . 78% vs . 62%, P=0.223), papilledema (CSF vs . VSS vs . ONSF: 71% vs . 86% vs . 77%, P=0.192), whilst visual acuity changes favored venous stenting (CSF vs . VSS vs . ONSF: 55% vs . 69% vs . 44%, P=0.037). There was a significantly lower rate of subsequent procedures with venous stent placement (CSF vs . VSS vs . ONSF: 37% vs . 13% vs . 18%, P vs . VSS vs . ONSF: 13% vs . 8% vs . 14%, P=0.28). Subgroup analysis of lumbar-peritoneal vs . ventriculoperitoneal shunts found no differences in symptom improvements, complications and subsequent procedure rates. Conclusions: Our findings suggest that dural venous sinus stenting may be a viable alternative to traditional surgical interventions in patients who are refractory to medical treatment. %U https://aes.amegroups.org/article/view/4345 %V 3 %P 26 %@ 2520-4122